|
KMID : 0387719950060010021
|
|
Korean Journal of Blood Transfusion
1995 Volume.6 No. 1 p.21 ~ p.28
|
|
|
Evaluation for the Sensitivity of LISS in Antiglobulin test
|
|
|
|
|
Abstract
|
|
|
The association rate of antibody with antigen has been reported to be greatly increased by lowering ionic strength. Low-ionic strength salt solution(LISS) method has been used for the detection of various
alloantibodies. To investigate the sensitivity of LISS in indirect antiglobulin test, a comparison study of LISS with saline and albumin methods was conducted. A total of 32 patients' samples requested for
indirect antiglobulin test were evaluated. Out of 32 patients with clinical immune hemolytic anemia, 11(34.3%) were positive in 37℃ saline antiglobulin test, 18(56.2%) in albumin antiglobulin test, 23(71.8%) in LISS antiglobulin test
respectively.
These results were statistically analyzed using non parametric Page's test for ordered alternatives. LISS method is more sensitive than 37℃ saline method or albumin method significantly (p<0.01).
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|